Licorice-derived ingredient
Monoammonium Glycyrrhizinate: The Licorice Compound in Glyco Reset and Your Blood Pressure
Monoammonium glycyrrhizinate is a licorice-derived ingredient listed in the 18th slot of the Glyco Reset blend, with no amount printed. Sloan Kettering calls high blood pressure with low potassium the most common licorice side effect. We found no source that names this exact salt.
Written by the Glyco Reset label deskUpdated
The name01
What is monoammonium glycyrrhizinate?
Monoammonium glycyrrhizinate is a salt of glycyrrhizin, the sweet compound in licorice root, and the label lists it as a licorice-derived ingredient.
It is the eighteenth of twenty-one names in the Glyco Reset blend. The label gives no amount, only the 200 mg total for the whole list.
A careful reader should note a gap. Every official page we read talks about licorice or glycyrrhizin, and none talks about this ammonium salt. We cannot assume the salt behaves the same, and we cannot assume it does not (MSK, Licorice (About Herbs)) (NCCIH, Licorice Root).
Blood pressure02
Can a licorice supplement raise blood pressure?
Yes, licorice with glycyrrhizin can raise blood pressure, and Sloan Kettering names high blood pressure with low potassium as its most common side effect.
Doctors call this hypokalemic hypertension, meaning pressure up and blood potassium down. Sloan Kettering links moderate amounts taken over time to it and describes a severe case in a 79-year-old woman (MSK, Licorice (About Herbs)).
NCCIH goes further. It says glycyrrhizin can cause an irregular heartbeat and, with large or long-term use, cardiac arrest. Even small amounts have been tied to serious effects in people with high blood pressure, heart or kidney conditions, or a high-salt diet (NCCIH, Licorice Root).
These sources describe licorice products, not Glyco Reset. The label's glycyrrhizinate amount is unprinted, so its share cannot be compared with any of those reports.
Potassium03
How does glycyrrhizin affect potassium?
Lost potassium is the link between glycyrrhizin and high blood pressure: potassium falls, and pressure and heart rhythm can follow.
Low potassium is the "hypokalemic" in the term above. Sloan Kettering lists it together with the blood pressure rise (MSK, Licorice (About Herbs)). NCCIH's page names heartbeat trouble, and a reference title there points to low potassium, but its body text does not explain the mechanism, so we stay with the facts both pages state.
- Salt in the diet matters: NCCIH notes small amounts hit harder with a high-salt intake.
- Ask your doctor about a potassium check if you take a diuretic.
- Tell your care team if you notice swelling, weakness or a pounding heartbeat.
Safety limits04
Is licorice root safe, and is there a safe daily amount?
NCCIH names no safe daily amount of licorice, so safety depends on the person and the product.
It also warns that licorice interacts with corticosteroids, and that eating about 250 g of licorice a week during pregnancy is unsafe (NCCIH, Licorice Root). Sloan Kettering also notes that DGL, a licorice form made without glycyrrhizin, is free of that compound (MSK, Licorice (About Herbs)).
The Glyco Reset label names a glycyrrhizinate, not DGL. The warning text printed on your own bottle is not in what we have, so read it before the first dropper.
| Question | Sources (MSK, NCCIH) | Glyco Reset label |
|---|---|---|
| Most common side effect | High blood pressure with low potassium | Not shown |
| Safe daily amount | None given | Amount not shown |
| Named compound | Licorice, glycyrrhizin | Monoammonium glycyrrhizinate |
| Glycyrrhizin removed (DGL) | Free of glycyrrhizin | Not stated |
Medicine check05
Which medicines clash with licorice?
Sloan Kettering lists diuretics, cardiac glycoside heart medicines, blood pressure drugs, insulin, metformin and warfarin as medicines that can clash with licorice.
NCCIH adds corticosteroids (MSK, Licorice (About Herbs)) (NCCIH, Licorice Root). Show the label to a pharmacist if you take any of them. Keep taking prescribed medicine and tell your doctor and pharmacist about every supplement (MedlinePlus, Metformin).
Only blood tests diagnose diabetes or prediabetes (NIDDK, Diabetes Tests & Diagnosis). Severe low blood sugar, fainting or a seizure is an emergency: call 911 (Mayo Clinic, Hypoglycemia).
Why these questions: (Mayo Clinic, Hypoglycemia) (MedlinePlus, Metformin) (ADA, Vitamins, Minerals, and Supplements (diabetes.org)) (NCCIH, Diabetes and Dietary Supplements) (MSK, Licorice (About Herbs)) (LiverTox, Green Tea). A checklist, never a clearance: only your doctor or pharmacist can say a supplement is right for you.
Reading on06
What should you read next about the blend?
Read the blend as a whole, because the licorice caution sits beside caffeine and herb cautions on the same label.
The ingredients page lists every name, the medicine check gathers the interaction points, and the side effects page covers warning signs. The proprietary blend page explains why no amount appears. If you order, confirm the price, shipping and guarantee at checkout.
FAQ07
Licorice and glycyrrhizinate: questions people ask
Is monoammonium glycyrrhizinate the same as licorice?
It is a licorice-derived salt of glycyrrhizin, the sweet compound in licorice root. Official pages we read cover licorice and glycyrrhizin, not this salt, so we cannot say the salt acts the same way.
How much glycyrrhizinate is in Glyco Reset?
The label does not say. Monoammonium Glycyrrhizinate is one of twenty-one names inside a 200 mg blend total with no split, so each name is below 200 mg and the exact share is unknown.
Does licorice lower potassium?
Sloan Kettering lists low potassium alongside high blood pressure as the most common licorice side effect. If you take a diuretic, ask your doctor whether a potassium check makes sense.
Who should avoid licorice supplements?
NCCIH links even small amounts to serious effects in people with high blood pressure, heart or kidney conditions or high salt intake. Corticosteroid users and pregnant people should ask a doctor first.
Can licorice affect heart rhythm?
NCCIH says glycyrrhizin can cause an irregular heartbeat and, with large or long-term use, cardiac arrest. Report a pounding or uneven pulse to a doctor and call 911 for fainting.
What is DGL licorice?
DGL is licorice with glycyrrhizin removed, according to Sloan Kettering. Glyco Reset names a glycyrrhizinate, so the DGL description does not apply to the label.
Is licorice safe with metformin or insulin?
Sloan Kettering lists insulin and metformin among medicines that can clash with licorice. Keep taking prescribed medicine, and show the label to a pharmacist before the first dropper.
Who wrote this08
Written and reviewed by
Pages built from the bottle label and linked NIH, CDC, FDA, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is the information site of a U.S. retail partner for Glyco Reset. It is not the manufacturer, and it is not the brand's sales page. We earn money when you buy through our order links.
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